ecklonia maxima skin COMPOSITION AND INFORMATION ON INGREDIENTS Raw material: Fresh material from Ecklonia maxima 34.26% Additives: Preservatives and inert materials 65.74% 3. It has shown 45.57% ROS scavenging ability and 49.33% inhibition of DNA damage at 250 μM concentrations (Heo et al., 2010). The potential antioxidant activities of three phlorotannins (phloroglucinol, eckol, and dieckol) purified from E. cava is reported to exhibit notable radical scavenging activities; in particular, eckol has been found to exhibit a superior scavenging activity for free radicals and inhibit DNA damage. In France, it is in the upper sublittoral zone and is harvested around the coast of Brittany and adjacent islands. In another laboratory-scale trial, Ecklonia maxima, Lessonia flavicans and Durvillaea potatorum adsorbed copper, nickel, lead, zinc and cadmium ions, though to varying extents depending on the seaweed type and metal ion concentration. It soothes itchy, irritated skin and can be used daily as required. Among them, brown algae serve as an important bioresource of antioxidative phlorotannins with significant pharmaceutical potential. Some phlorotannins have been identified as the bioactive components in Ecklonia species such as Ecklonia cava, Ecklonia kurome, and Ecklonia stolonifera (Ham et al., 2007). Ascophyllum is found in cold waters of the Northern Hemisphere. Diphlorethohydroxycarmalol isolated from I. okamurae has also been studied for its photoprotective ability in UVB (50 mJ cm− 2) irradiated HDF cells. Therefore, wide range of potential metabolites has been evaluated against oxygen-induced damage and hence lowers the risk of human chronic diseases. They are found both in the eulittoral and upper sublittoral zones. By continuing you agree to the use of cookies. 25g. 33.3), a new compound isolated from the methanol extract of E. cava, a brown alga, collected offshore in Jeju Island by Ham et al. It is reported that sun-damaged skin shows significantly elevated levels of active gelatinases (MMP-2 and MMP-9) than intrinsically aged skin (Chung et al., 2001). Phlorotannins derived from brown seaweeds and their chemical structures. Also known as brown algae or brown seaweed, ecklonia cava has been linked to some powerful health benefits to its high levels of antioxidants, anti-inflammatories, and phloroglucinols. For alginate extraction, they are regarded as the raw material of last resort. 1.4 shows the distribution of wild brown seaweeds around the world. (A) The disaccharide repeating unit [4)-α-l-Fucp(2,3di-OSO3−)-(1 → 3)-α-l-Fucp(2OSO3−)-(1] of a fraction of A. nodosum fucoidan representing the most abundant structural feature of fucoidans from both A. nodosum and F. vesiculosus. XXXV. (1997) and Hupel et al. Sargassum is collected on the south coast of Java, Indonesia, and the Philippines. Paula Begoun is the best-selling author of 20 books about skincare and makeup. Numbers of studies have shown the radical scavenging potential of phlorotannins isolated from marine brown algae. In the 1950s, China developed a way of cultivating S. japonica on long ropes suspended in the ocean, and this became a widespread source of income for large numbers of coastal families. Rothman et al. The species Ecklonia and Eisenia are the mostly studied brown algae for the biological activities associated with phlorotannins. This UVB radiation induces the overproduction of ROS which interacts with cellular DNA, proteins, and lipids to alter their cellular functions (Heo et al., 2010). Therefore, these phlorotannins have been isolated from algae and investigated for their possible application in reducing the photodamage of the skin. Although much of these cultivated seaweeds are used for direct food consumption, they also provide a strong foundation for the thriving alginate industry in China. It is sensitive to water temperature and does not withstand a rise above 20°C. L. saccharina often grows in close association with L. digitata, and is sometimes harvested at the same time. ROS stimulates mitogen-activated protein kinases that phosphorylate transcription factor AP-1, which in turn results in upregulation of MMPs that contribute for the degradation of skin collagen ultimately leading to skin ageing (Fisher et al., 1996; Rittié and Fisher, 2002). These in vitro studies bring front the scientific proof that phloroglucinol from marine algae can be recommended as a medicinal agent to reduce the risk of metastasis and inflammation-related diseases. Therefore, they have received the greatest attention and have been investigated extensively since they are high free radical scavengers in nature and less toxic than synthetic antioxidants such as BHA and BHT (Jung et al., 2008). Natural Skin Therapy Check Collection. 33.2. The studies listed focus on both hydroalcoholic extracts and purified fractions of a few eckols. A detailed account of the various biological activities including free radical scavenging activity of phlorotannins from Ecklonia species has been reported earlier. At present, Sargassum is not subjected to mass cultivation, but efforts to develop farming technologies are under way. These results indicated that sulfated galactan from P. haitanensis has a beneficial effect in vivo on aging models. They exhibit a wide variety in shape and form. 33.3. It grows in parts of Asia. Lessonia trabeculata grows in the sublittoral between 1 and 20 m in depth. High-level aflatoxin exposure produces acute hepatic necrosis, subsequently resulting in cirrhosis, and/or carcinoma of the liver. Click once to buy - Wait for … 33.2) were isolated from E. cava by Ryu et al. Ecklonia Maxima Seaweed & Botanicals. In Chile, open-sea-cultured hybrids of Macrocystis produced 66 kg/m culture rope (Westermeier et al., 2011) while landings of Macrocystis in Mexico are approximately 20,000 tons (Robledo, 2006). And also they have shown that the DNA damage due to UVB irradiation was also inhibited by 57.8% with the treatment of 50 μM dieckol. Bioassay-guided fractionation of the ethyl acetate fraction of Ecklonia stolonifera revealed several phlorotannins, such as phloroglucinol, eckstolonol, eckol, phlorofucofuroeckol A, and dieckol. J. Mancini-Filho, ... A.M.O. L. nigrescens grows in thick belts in the rocky lower eulittoral zone, where its massive holdfast allows it to survive the rough waters in which it thrives. In addition, this review highlights that species mainly devoted to direct human food have been investigated. Moreover, Ko et al. About the Experts. (2003) studied the fucoidan derived from brown algae and other common fucoidans (Fig. Biomass production of natural beds in the tropics is largely unknown but can reach 15.6 kg/m2 (wet weight) in the Philippines (Marquez et al., 2014). Fig. 2012 for further details). A 14 kDa protein isolated from the alga Porphyra has been observed to be effective against APAP-induced liver injury, demonstrating promising results in terms of caspase activity and DNA fragmentation (Hwang et al., 2011). Ecklonia Cava is a type of seaweed which is known to be one of the highest sources of phloroglucinols, a type of antioxidant compound that appears to be unique to sea plants. (2010) estimated the biomass of Ecklonia maxima found in deep waters of some areas in South Africa at ∼16.1 kg wet wt/m 2. Oxidative stress is considered to be a causal factor in atherosclerosis progression. Globally, Norway and Chile are the two countries where wild seaweeds are most abundant due to their long coastal lines and suitable environmental conditions. Ecklonia grows in South Africa, and Laminaria digitata is mainly from France and Iceland. (2010) estimated the biomass of Ecklonia maxima found in deep waters of some areas in South Africa at ∼16.1 kg wet wt/m2. PubMed:Enhancing growth, phytochemical constituents and aphid resistance capacity in cabbage with foliar application of eckol--a biologically active phenolic molecule from brown seaweed. This amazing seaweed is harvested only on the west coast of South Africa. The phlorotannins eckol and dieckol that were first isolated from Ecklonia species possess oligomeric polyphenol of phloroglucinol unit. Fucodiphlorethol G (Fig. Ecklonia maxima is one of the most preferred sources of sea kelp for stimulating plant growth. HS Baby Care Range uses the natural vitamins, minerals, amino acids, enzymes and natural bacteria fighting components contained in Ecklonia Maxima Seaweed as a barrier to help protect your baby’s skin whilst it has not developed enough to adequately protect itself. Zhang et al. It grows on rocky bottoms where its holdfast can become established, and can be found as large underwater forests, with plants rising to and growing along the surface, at times up to 20 m in length. Taxonomic Distribution and Geographic Origin of Species Tested for the Antiallergic Activity of Crude/Semipurified Extracts Suspected of Containing Phenols and of Purified Phlorotannin Fractions, J.A. Brown algae containing fucoidan, H.R.B. (2011) have shown that brown algae are more tolerant to UVB irradiation due to the presence of phlorotannins. Ingredients: Purified Water, Ecklonia Maxima Extract, glucose, glucose oxidase, lactoperoxidase, citric … (A) Laminaria hyperborea; (B) Ascophyllum nodosum; (C) Macrocystis pyrifera; (D) Lessonia nigrescens; (E) Laminaria digitata; (F) Saccharina japonica; (G) Ecklonia maxima. For skin care, the uncrowned king of seaweeds is the legendary Ecklonia Maxima, from which we derive Algaeron’s purely natural key ingredient. Natural Baby Care Check Collection. 33.4. Laminaria hyperborea is mainly from Norway, the United Kingdom, Ireland, and France. L. digitata grows in the upper sublittoral zone in rocky, wave-exposed localities, and it is well adapted to this because of its flexible stipe and divided blades. In France, L. digitata is the main raw material for the alginate industry. extracts are manufactured from brown seaweeds such as Ascophyllum nodosum (A. nodosum), Ecklonia maxima (E. maxima), Laminaria spp., or Sargassum spp. Ecklonia maxima, better known as kelp. We use cookies to help provide and enhance our service and tailor content and ads. (2011) evaluated the antiatherogenic effect of hydrophilic extracts and phenolic-rich fractions from H. incrassata using Apo E −/− mice on a high fat diet, which was supplemented with 550 mg lyophilized seaweed/kg/day for 8 weeks. (2004) investigated the effect of sulfated galactan from Porphyra haitanensis on aging in Kunming mice by intraperitoneal administration. Some active components, including several phlorotannins, such as eckstolonol, eckol, phlorofucofuroeckol, and dieckol, isolated from E. stolonifera exhibited hepatoprotective and cytotoxic effects with a half-maximum effective concentration (EC50) at around 62.0–79.2 μg/mL. Macrocystis angustifolia has been cultivated on an experimental scale in South Africa with a view to eventually growing it for alginate production or abalone feed. (2004) have shown strong ROS inhibitory activity of phlorotannins; eckol (IC50 4.04 μM) and phlorofucofuroeckol A (IC50 3.8 μM) isolated from Ecklonia stolonifera on rat kidney homogenates of freshly killed male Wistar rats. In recent years, alginate producers in China began importing Chilean and Peruvian medium G seaweeds such as Lessonia nigrescens, which can yield alginates suitable for the food ingredient market in the United States and EU. North of this latitude M. pyrifera is mostly limited to rare wave-protected areas along the continental Chilean littoral (Villouta and Santelices, 1984). Diphlorethohydroxycarmalol and 6,6-bieckol isolated from Ishige okamurae (Zou et al., 2008); fucodiphloroethol G and dieckol isolated from Ecklonia cava (Li et al., 2009) have shown of 77.2%, 78.9%, 75.6%, and 84.3% ROS inhibition at 50 μM, respectively, in H2O2-induced RAW264.7 cells. Quantity in pack: 1. In the late 1980s, production fell as some farmers switched to the more lucrative but risky farming of shrimp. 1.3 shows the harvest of wild brown seaweeds in 2014. Structures of phlorotannins from Ecklonia cava (1: dieckol; 2: 1-(3′,5′-dihydroxyphenoxy)-7-(2″,4″,6″-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4-dioxin). As it is evident that unregulated expression of MMPs leads to the photoaging, many research groups are emphasizing their research goals to check the ability of marine-derived phlorotannins as potential antiphotoaging agents. Experimental cultivation of Ecklonia in South Africa has been successful, with growth of young plants on rafts. Se-Kwon Kim, S.W.A. In this study, it has been suggested that fucofuroeckol-A and eckol exhibited a significant inhibitory activity on the NF-κB expression and also they had a considerable inhibitory effect on AP-1 expression, thus inhibiting the expression of MMP-2 and MMP-9 via blocking the transcription of both NF-κB and AP-1 (Lee, 2010). Macrocystis forms dense subtidal forests in many locations, which include the North and South Pacific coasts and isolated areas in South Africa, New Zealand, and Australia. Lessonia species are found in both Northern and Southern Hemispheres, but they are only collected in northern Chile where they grow on offshore shoals and are torn off in rough weather. Dermikelp®. M. pyrifera is harvested from offshore beds that stretch from Monterey in California, United States, to Bahia Asuncion in Baja California Sur, Mexico. Dieckol was found to be the most potent phlorotannin to protect the cells from UVB irradiation (50 mJ cm− 2). Made from natural sea harvested Ecklonia Maxima beach cast kelp. Phlorotannins are oligomeric compounds using phloroglucinol (1,3,5-trihydroxybenzene) as a basic unit. By the examination of 1H and 13C NMR data, it was found that the structure of the compound is similar to that of trimeric phlorotannin triphlorethol-A (Fig. Overview Information Ecklonia cava is a type of algae that is used as food and medicine. US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: cosmetic ingredient for skin conditioning. Natural metabolites obtained from marine seaweeds prove to be abundant resources with chemical diversity, and among them, phlorotannins are studied most for their biological activities. Figure 1.4. In Kilmore Quay, Ireland, an S. muticum bed was estimated to have an average biomass of 487 tons (wet weight) (Kraan, 2008). Vetlomar™ EQ Allergy Itch Relief Cream contains the patented CEM-K active ingredient, sustainably sourced from the giant sea kelp species, Ecklonia maxima, to manage a horses allergic skin reactions. Raghavendran, ... S. Rekha, in Functional Ingredients from Algae for Foods and Nutraceuticals, 2013. 1.2 illustrates the main types of brown seaweeds used for alginate production. This in vitro study also reports that these phlorotannins were able to promote osteosarcoma differentiation by increasing alkaline phosphatase (ALP) activity, mineralization, total protein, and collagen synthesis (Ryu et al., 2009b). Minh Hong Thi Nguyen, ... Se-Kwon Kim, in Advances in Food and Nutrition Research, 2011. Radical scavenging activities of phlorotannins from brown algae. Moreover, the ROS that includes hydrogen peroxide, hydroxyl radical, and superoxide anion is involved in metabolic diseases, especially chronic inflammation. On the other hand, reports suggest that some other brown alga contain higher amount of phloroglucinol (Koivikko et al., 2005) and have exhibited several medicinally beneficial effects in vitro. Figure 1.2. Figure 1.3. It has been suggested that phlorotannins derived from marine brown algae might be useful in the development of novel hepatoprotective agents (Kim et al., 2005). Raw material: Fresh material from Ecklonia maxima 34.26% Additives: Preservatives and inert materials 65.74% 3. A novel polysaccharide named coccolith matrix acidic polysaccharide (CMAP) was isolated from the coccolith of a coccolithophorid alga, Pleurochrysis haptonemofera, by Ozaki et al. In vitro studies on methanol extract from marine alga Corallina pilulifera (CPM) have revealed that CPM has the ability to prevent UV-induced oxidative stress and also the expressions of MMP-2 and MMP-9 in HDF cells. Moreover, Kraan et al. The latter species appears to have a higher biomass yield (12.7 kg/m culture rope) (Hwang et al., 2013). We explored variation in preharvest conditions in a small study of two Namibian kelps (Laminaria pallida and Ecklonia maxima), and found that iodine content was lowest in sun-bleached blades (514 +/- 42 microg/g), and highest amount in freshly cut juvenile blades (6571 +/- 715 microg/g). Investigations to find out natural products that promote Ca-mineralization are interesting nowadays. Cortisone free. Interestingly, this in vitro study has revealed that the phlorotannis did not exhibit any cytotoxicity on the cells and has the MMP inhibitory effect almost same to that of doxycyclin (a commercial MMP inhibitor). Moreover, the phloroglucinol has exhibited anti-inflammatory activity by expression levels of TNF-α, IL-1β, IL-6, and PGE2 in macrophages RAW264.7 (Kim and Kim, 2010). Brown algae flourish in temperate to subpolar regions where they exhibit the greatest diversity in species and morphological expression. Canopy- and habitat-forming brown algae are often the most productive in many coasts around the world. After successfully developing kelp-based products for use in agriculture, he discovered that sea kelp could have benefits for skin too. More lucrative but risky farming of shrimp of Ecklonia maxima, Koppie Alleen, De Hoop, 2010 diseases as. The potential of Hydroclathrus to produce fertilizer Hot Spot Spray offer Relief from,... That brown algae for Foods and Nutraceuticals, 2013 ) in brown algae serve as an alternate animal model.! 280–320 nm ) radiation of the skin from 22 to 27 % /

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